Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Strength of tonic T cell receptor signaling instructs T follicular helper cell-fate decisions.

Bartleson, Juliet M; Viehmann Milam, Ashley A; Donermeyer, David L; Horvath, Stephen; Xia, Yu; Egawa, Takeshi; Allen, Paul M.

Nat Immunol ; 21(11): 1384-1396, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32989327

2.

A RORÎ³t⁺ cell instructs gut microbiota-specific T_reg cell differentiation.

Kedmi, Ranit; Najar, Tariq A; Mesa, Kailin R; Grayson, Allyssa; Kroehling, Lina; Hao, Yuhan; Hao, Stephanie; Pokrovskii, Maria; Xu, Mo; Talbot, Jhimmy; Wang, Jiaxi; Germino, Joe; Lareau, Caleb A; Satpathy, Ansuman T; Anderson, Mark S; Laufer, Terri M; Aifantis, Iannis; Bartleson, Juliet M; Allen, Paul M; Paidassi, Helena; Gardner, James M; Stoeckius, Marlon; Littman, Dan R.

Nature ; 610(7933): 737-743, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36071167

3.

Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC.

Persaud, Stephen P; Parker, Chelsea R; Lo, Wan-Lin; Weber, K Scott; Allen, Paul M.

Nat Immunol ; 15(3): 266-74, 2014 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-24487322

4.

c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells.

Chou, Chun; Pinto, Amelia K; Curtis, Jonathan D; Persaud, Stephen P; Cella, Marina; Lin, Chih-Chung; Edelson, Brian T; Allen, Paul M; Colonna, Marco; Pearce, Erika L; Diamond, Michael S; Egawa, Takeshi.

Nat Immunol ; 15(9): 884-93, 2014 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-25029552

5.

The TCR Takes Some Immune Responsibility.

Viehmann Milam, Ashley A; Allen, Paul M.

Immunity ; 47(5): 803-804, 2017 11 21.

Artigo em Inglês | MEDLINE | ID: mdl-29166579

6.

How the TCR balances sensitivity and specificity for the recognition of self and pathogens.

Morris, Gerald P; Allen, Paul M.

Nat Immunol ; 13(2): 121-8, 2012 Jan 19.

Artigo em Inglês | MEDLINE | ID: mdl-22261968

7.

A voltage-gated sodium channel is essential for the positive selection of CD4(+) T cells.

Lo, Wan-Lin; Donermeyer, David L; Allen, Paul M.

Nat Immunol ; 13(9): 880-7, 2012 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-22842345

8.

Publisher Correction: A RORÎ³t⁺ cell instructs gut microbiota-specific T_reg cell differentiation.

Kedmi, Ranit; Najar, Tariq A; Mesa, Kailin R; Grayson, Allyssa; Kroehling, Lina; Hao, Yuhan; Hao, Stephanie; Pokrovskii, Maria; Xu, Mo; Talbot, Jhimmy; Wang, Jiaxi; Germino, Joe; Lareau, Caleb A; Satpathy, Ansuman T; Anderson, Mark S; Laufer, Terri M; Aifantis, Iannis; Bartleson, Juliet M; Allen, Paul M; Paidassi, Helena; Gardner, James M; Stoeckius, Marlon; Littman, Dan R.

Nature ; 610(7931): E7, 2022 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-36151471

9.

Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine.

Hsieh, Samantha; Porter, Nathan T; Donermeyer, David L; Horvath, Stephen; Strout, Gregory; Saunders, Brian T; Zhang, Nan; Zinselmeyer, Bernd; Martens, Eric C; Stappenbeck, Thaddeus S; Allen, Paul M.

J Immunol ; 204(4): 1035-1046, 2020 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-31900343

10.

Phase-variable bacteria simultaneously express multiple capsules.

Hsieh, Samantha A; Donermeyer, David L; Horvath, Stephen C; Allen, Paul M.

Microbiology (Reading) ; 167(7)2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-34224345

11.

An endogenous peptide positively selects and augments the activation and survival of peripheral CD4+ T cells.

Lo, Wan-Lin; Felix, Nathan J; Walters, James J; Rohrs, Henry; Gross, Michael L; Allen, Paul M.

Nat Immunol ; 10(11): 1155-61, 2009 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-19801984

12.

Tuning T Cell Signaling Sensitivity Alters the Behavior of CD4⁺ T Cells during an Immune Response.

Milam, Ashley A Viehmann; Bartleson, Juliet M; Donermeyer, David L; Horvath, Stephen; Durai, Vivek; Raju, Saravanan; Yu, Haiyang; Redmann, Veronika; Zinselmeyer, Bernd; White, J Michael; Murphy, Kenneth M; Allen, Paul M.

J Immunol ; 200(10): 3429-3437, 2018 05 15.

Artigo em Inglês | MEDLINE | ID: mdl-29618523

13.

L-Myc expression by dendritic cells is required for optimal T-cell priming.

KC, Wumesh; Satpathy, Ansuman T; Rapaport, Aaron S; Briseño, Carlos G; Wu, Xiaodi; Albring, Jörn C; Russler-Germain, Emilie V; Kretzer, Nicole M; Durai, Vivek; Persaud, Stephen P; Edelson, Brian T; Loschko, Jakob; Cella, Marina; Allen, Paul M; Nussenzweig, Michel C; Colonna, Marco; Sleckman, Barry P; Murphy, Theresa L; Murphy, Kenneth M.

Nature ; 507(7491): 243-7, 2014 Mar 13.

Artigo em Inglês | MEDLINE | ID: mdl-24509714

14.

LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens.

Yokoyama, Christine C; Baldridge, Megan T; Leung, Daisy W; Zhao, Guoyan; Desai, Chandni; Liu, Ta-Chiang; Diaz-Ochoa, Vladimir E; Huynh, Jeremy P; Kimmey, Jacqueline M; Sennott, Erica L; Hole, Camaron R; Idol, Rachel A; Park, Sunmin; Storek, Kelly M; Wang, Caihong; Hwang, Seungmin; Viehmann Milam, Ashley; Chen, Eric; Kerrinnes, Tobias; Starnbach, Michael N; Handley, Scott A; Mysorekar, Indira U; Allen, Paul M; Monack, Denise M; Dinauer, Mary C; Doering, Tamara L; Tsolis, Renee M; Dworkin, Jonathan E; Stallings, Christina L; Amarasinghe, Gaya K; Micchelli, Craig A; Virgin, Herbert W.

J Biol Chem ; 293(16): 6022-6038, 2018 04 20.

Artigo em Inglês | MEDLINE | ID: mdl-29496999

15.

Taking a toll road to better vaccines.

Morley, Sharon Celeste; Allen, Paul M.

Immunity ; 28(5): 602-4, 2008 May.

Artigo em Inglês | MEDLINE | ID: mdl-18482564

16.

The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality.

Cemerski, Saso; Das, Jayajit; Giurisato, Emanuele; Markiewicz, Mary A; Allen, Paul M; Chakraborty, Arup K; Shaw, Andrey S.

Immunity ; 29(3): 414-22, 2008 Sep 19.

Artigo em Inglês | MEDLINE | ID: mdl-18760640

17.

Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells.

Hong, Jinsung; Persaud, Stephen P; Horvath, Stephen; Allen, Paul M; Evavold, Brian D; Zhu, Cheng.

J Immunol ; 195(8): 3557-64, 2015 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-26336148

18.

Themis imposes new law and order on positive selection.

Allen, Paul M.

Nat Immunol ; 10(8): 805-6, 2009 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-19621038

19.

The ability to rearrange dual TCRs enhances positive selection, leading to increased Allo- and Autoreactive T cell repertoires.

Ni, Peggy P; Solomon, Benjamin; Hsieh, Chyi-Song; Allen, Paul M; Morris, Gerald P.

J Immunol ; 193(4): 1778-86, 2014 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-25015825

20.

Self-peptides in TCR repertoire selection and peripheral T cell function.

Lo, Wan-Lin; Allen, Paul M.

Curr Top Microbiol Immunol ; 373: 49-67, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-23612987

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